Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene
β Scribed by Poltorak, A.
- Book ID
- 111966153
- Publisher
- American Association for the Advancement of Science
- Year
- 1998
- Tongue
- English
- Weight
- 269 KB
- Volume
- 282
- Category
- Article
- ISSN
- 0036-8075
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract C3H/HeJ(C3H) mice are approximately 50βfold more susceptible to liverβtumor induction than C57BL/6J(B6) mice. This difference in susceptibility is a consequence of allelic differences in hepatocarcinogen sensitivity(__Hcs__) genes that control the growth of preneoplastic lesions in the
To assess genetic factors determining sensitivity to streptozotocin-induced diabetes in inbred strains of mice, a genetic analysis of streptozotocin-sensitive C57BL/6J and streptozotocin-resistant C3H/HeJ mice was performed. One week after a single dose of streptozotocin (200 mg/kg body weight), dif