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Defective actin polymerization in patients with the Wiskott-Aldrich syndrome

✍ Scribed by F. Facchetti; L. Blanzuoli; W. Vermi; L.D. Notarangelo; D.L. Nelson


Book ID
117326090
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
251 KB
Volume
35
Category
Article
ISSN
0161-5890

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The Wiskott-Aldrich syndrome (WAS) is a rare X-linked recessive disorder characterized by eczema, thrombocytopenia, and immunodeficiency. An allelic variant of the disease is characterized by isolated thrombocytopenia (XLT). The gene responsible for WAS/XLT (WASP) encodes for a 502 amino acid protei