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Deep brain stimulation: indications and applications

✍ Scribed by Bieber, Allan J.; Duffy, Penelope S.; Lee, Kendall H


Publisher
Pan Stanford Publishing
Year
2017
Tongue
English
Leaves
474
Category
Library

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✦ Synopsis


Deep brain stimulation (DBS) is a widely used therapy for movement disorders such as Parkinson's disease, essential tremor, and dystonia. Its therapeutic success has led to the application of DBS for an increasing spectrum of conditions. However, the fundamental relationships between neural activation, neurochemical transmission, and clinical outcomes during DBS are not well understood.

Drawing on the clinical and research expertise of the Mayo Clinic Neural Engineering Laboratories, this book addresses the history of therapeutic electrical stimulation of the brain, its current application and outcomes, and theories about its underlying mechanisms. It reviews research on measures of local stimulation–evoked neurochemical release, imaging research on stimulation-induced neural circuitry activation, and the state of the art on closed-loop feedback devices for stimulation delivery.

✦ Table of Contents


Content: Part I. Introduction to deep brain stimulation --
part II. Clinical applications --
part III. Research on mechanisms of DBS and neuromodulation.

✦ Subjects


Brain stimulation.;Brain stimulation;Therapeutic use.;Deep Brain Stimulation.


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