Deep Brain Stimulation and Epilepsy

✍ Scribed by Luders, Hans O

• Publisher: CRC Press
• Year: 2020
• Tongue: English
• Leaves: 385
• Edition: 1st edition
• Category: Library

✦ Synopsis

Deep brain stimulation has been used effectively for many years to treat patients suffering from Parkinson's disease. Now, neurologists and neurosurgeons are using electric pulse generators to block abnormal activity, i.e. epileptic fits. Promising research results indicate that electric pulses implanted deep in the brain can affect neurocircuitry and help stop oncoming seizures. Supplying a solid background on brain stimulation and its application to epilepsy, Deep Brain Stimulation and Epilepsy provides a historical overview, explores pathogenesis of brain stimulation, discusses animal experiments and human studies, and explores future prospects of brain stimulation for epileptic control. The editor and his team of contributors distill information drawn directly from the literature into one convenient resource.

✦ Table of Contents

Cover......Page 1
Title Page......Page 2
Copyright Page......Page 3
Table of Contents......Page 4
Contributors......Page 8
I Historical overview: brain stimulation and epilepsy......Page 14
1 Brain stimulation and epilepsy: basic overview and novel approaches......Page 16
II Pathogenesis of brain stimulation: animal studies......Page 32
2 The basal ganglia: an overview......Page 34
3 The subthalamic nucleus: anatomy and neurophysiology......Page 42
4 Brain stimulation and epilepsy: electrical stimulus characteristics......Page 58
5 Electrically excitable nerve elements: excitation sites in peripheral and central stimulation......Page 68
6 Control of neuronal activity by electrical fields: in vitro models of epilepsy......Page 80
7 The nigral control of epilepsy: basal ganglia circuitry as a substrate for seizure control......Page 100
8 High frequency direct cortical electrical stimulation: an animal model of induced acute focal seizures......Page 110
III Pathogenesis of brain stimulation: human studies......Page 116
9 Cortico-coritcal evoked potentials......Page 118
10 Repetitive transcranial magnetic stimulation......Page 126
11 High frequency subthalamic nucleus stimulation......Page 142
12 Cortical-evoked potentials from deep brain stimulation......Page 156
13 EEG recording from the subthalamic nucleus in patients with epilepsy......Page 170
14 EEG and the anterior thalamic nucleus......Page 184
IV Effect of brain stimulation on epileptic seizures: animal experiments......Page 200
15 Absence seizures in the GAERS model: subthalamic nucleus stimulation......Page 202
16 Focal limbic seizures induced by kainic acid: effects of bilateral subthalamic nucleus stimulation......Page 212
17 Focal stimulation versus deep brain stimulation......Page 222
18 The anterior thalamus and the pentylenetetrazol (PTZ) model......Page 228
V Effect of brain stimulation on epileptic seizures: human studies......Page 258
19 Vagal nerve stimulation: surgical technique......Page 260
20 Vagal nerve stimulation: effects on seizures......Page 268
21 Therapeutic prospects and safety of transcranial magnetic stimulation in epilepsy......Page 276
22 Direct cortical electrical stimulation in the treatment of epilepsy......Page 288
23 Electrical neuromodulation of the epileptic focus in cases of temporal lobe seizures......Page 298
24 Anterior thalamic nucleus stimulation: surgical procedure......Page 312
25 Anterior thalamic nucleus stimulation: issues in study design......Page 318
26 Surgical procedure for subthalamic nucleus stimulation......Page 334
27 Subthalamic nucleus and substantia nigra pars reticulata stimulation: the Grenoble experience......Page 348
28 Subthalamic nucleus stimulation in patients with intractable epilepsy: the Cleveland experience......Page 362
VI Brain stimulation: future prospects......Page 370
29 The future of brain stimulation for seizure control......Page 372
Index......Page 376

✦ Subjects

Brain stimulation;Epilepsy;Evoked potentials (Electrophysiology);MEDICAL / General;MEDICAL / Neurology;Electronic books