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Deep Brain Stimulation in Tourette’s Syndrome

✍ Scribed by Linda Ackermans; Yasin Temel; Veerle Visser-Vandewalle

Book ID
104072042
Publisher
Springer-Verlag
Year
2008
Tongue
English
Weight
78 KB
Volume
5
Category
Article
ISSN
1933-7213

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✦ Synopsis

Tourette's Syndrome (TS) is a neuropsychiatric disorder characterized by motor and vocal tics, often associated with behavioral disorders. Symptoms often disappear before or during adulthood. The pathophysiology of TS is still a matter of considerable debate. Current knowledge of cortico-basal ganglia-thalamocortical circuits provide explanations for the beneficial effects of deep brain stimulation (DBS) on tics. When conservative treatment fails in patients with severe TS, DBS may be a therapeutic option. In 1999, thalamic DBS was introduced for intractable TS. Since then, multiple targets have been used in a small number of patients, including the globus pallidus pars interna and the nucleus accumbens. Inclusion and exclusion criteria have been formulated to identify good candidates for DBS.

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