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Deep brain stimulation in Tourette's syndrome

✍ Scribed by Rizma Jalees Bajwa; Alain J. de Lotbinière; Robert A. King; Bahman Jabbari; Susan Quatrano; Kimberly Kunze; Lawrence Scahill; James F. Leckman

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
144 KB
Volume
22
Category
Article
ISSN
0885-3185

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✦ Synopsis

Abstract

A 48‐year‐old man with severe, lifelong Tourette's syndrome (TS) characterized by forceful self‐injurious motor tics and obsessive‐compulsive disorder was treated with bilateral deep brain stimulation (DBS). The decision to treat was based on his progressive neurological impairment (left sided weakness secondary to spinal cord injury) because of his relentless, violent head jerks. Electrodes were implanted at the level of the medial part of the thalamus (centromedian nucleus, the substantia periventricularis, and the nucleus ventro‐oralis internus). DBS resulted in a substantial reduction of tics. These data show that bilateral DBS of the thalamus can have a good effect on severe tics in adult patients suffering from intractable TS. © 2007 Movement Disorder Society

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