## Abstract ## Background and Objectives Low tumor expression of the p27^Kip1^ protein, which is involved in cell cycle control and apoptosis, is considered a negative prognostic factor in different types of cancer. The aim of this study was to evaluate the clinical and pathological significance o
โฆ LIBER โฆ
Decreasing of p27Kip1and cyclin E protein levels is associated with progression from superficial into invasive bladder cancer
โ Scribed by Kamai, T; Takagi, K; Asami, H; Ito, Y; Oshima, H; Yoshida, K-I
- Book ID
- 111724487
- Publisher
- Nature Publishing Group
- Year
- 2001
- Tongue
- English
- Weight
- 182 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0007-0920
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Background and Objectives: p27Kip1 is an inhibitor of cyclindependent kinases and is speculated to be a potential prognostic indicator in numerous human cancers. We investigated expression of p27Kip1 along with cyclin D1 in gastric cancer to estimate the clinical utility of p27Kip1. Methods: Immunoh