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Decreased vesicular monoamine transporter 2 (VMAT2) and dopamine transporter (DAT) function in knockout mice affects aging of dopaminergic systems

โœ Scribed by Hall, F.S.; Itokawa, K.; Schmitt, A.; Moessner, R.; Sora, I.; Lesch, K.P.; Uhl, G.R.


Book ID
122261399
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
733 KB
Volume
76
Category
Article
ISSN
0028-3908

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The dose-and time-dependent changes of in vivo radioligand binding to the neuronal membrane dopamine transporter (DAT) and vesicular monoamine transporter type 2 (VMAT2) were examined in mouse brain after MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) administrations. Regional brain distributio