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Decreased urinary concentrations of type IV collagen in amyotrophic lateral sclerosis

✍ Scribed by S. Ono; T. Imai; S. Matsubara; K. Takahashi; K. Jinnai; T. Yamano; N. Shimizu


Book ID
109336982
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
604 KB
Volume
100
Category
Article
ISSN
0001-6314

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We analyzed the serum levels of type IV collagen, a major component of the basement membrane, during various stages of sporadic amyotrophic lateral sclerosis (ALS). Serum concentrations of type IV collagen increased significantly with the duration of illness. Findings indicate that the metabolism of