Serum type IV collagen increases with duration of amyotrophic lateral sclerosis
โ Scribed by Kouji Houi; Takaaki Kobayashi; Shuichi Kato; Soichiro Mochio; Kiyoharu Inoue
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 113 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0148-639X
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โฆ Synopsis
We analyzed the serum levels of type IV collagen, a major component of the basement membrane, during various stages of sporadic amyotrophic lateral sclerosis (ALS). Serum concentrations of type IV collagen increased significantly with the duration of illness. Findings indicate that the metabolism of type IV collagen and the basement membrane may be affected in the disease process of ALS.
๐ SIMILAR VOLUMES
To investigate the mechanical efficiency of surviving motor units of anterior tibial muscle in patients with amyotrophic lateral sclerosis (ALS), we studied motor unit action potentials, muscle force, and muscle fatigability in patients with ALS and controls using 25 min of low to moderate intensity