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Decreased microRNA(miR)-145 and increased miR-224 expression in T cells from patients with systemic lupus erythematosus involved in lupus immunopathogenesis

✍ Scribed by Lu, M-C.; Lai, N-S.; Chen, H-C.; Yu, H-C.; Huang, K-Y.; Tung, C-H.; Huang, H-B.; Yu, C-L.


Book ID
119833879
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
486 KB
Volume
171
Category
Article
ISSN
0009-9104

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Using radiolabeled interleukin-2 (IL-2), affinity cross-linking and binding assays revealed that the expression of intermediate-affinity IL-2 binding molecules (p70/75) on freshly prepared T cells from patients with systemic lupus erythematosus (SLE) was significantly decreased in comparison with th