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Decreased levels of protein kinase C enzyme activity and protein kinase C mRNA in primary colon tumors

โœ Scribed by Miriam F. Levy; Joanne Pocsidio; Jose G. Guillem; Kenneth Forde; Paul LoGerfo; I. Bernard Weinstein

Book ID
112678502
Publisher
Springer
Year
1993
Tongue
English
Weight
843 KB
Volume
36
Category
Article
ISSN
0012-3706

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Expression of multiple isoforms of prote
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## Abstract Previous studies have suggested that protein kinase C (PKC) may play an important role in colon carcinogenesis and that human colon tumors have less total PKC enzyme activity than normal tissue. Because PKC is a multigene family that enocodes for at least 11 distinct isofroms, in the st