Decreased expression and rare somatic mutation of the CIP1/WAF1 gene in human hepatocellular carcinoma
โ Scribed by Masaharu Furutani; Shigeki Arii; Hisashi Tanaka; Masahiro Mise; Mototaka Niwano; Tomika Harada; Hiroaki Higashitsuji; Masayuki Imamura; Jun Fujita
- Book ID
- 117468390
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 940 KB
- Volume
- 111
- Category
- Article
- ISSN
- 0304-3835
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
RNase H 0 reverse transcriptase (GIBCO-BRL, Gaithersburg, MD). ase chain reaction; SSCP, single-strand conformation polymorphism; mRNA, messenger p21 WAF1/CIP1 messenger RNA (mRNA) was amplified with the follow-RNA; cdk, cyclin dependent kinase.
The cytotoxicity of Doxorubicin and cis-dichloro-diammineplatinum (DDP) was evaluated in clones, obtained from a human ovarian cancer cell line transfected with a ternperaturesensitive p53 mutant, which express mutant p53 at 37ยฐC and wild-type-like p53 at 32ยฐC. DDP was equally active in cells not ex