✦ LIBER ✦

Decreased catalytic function with altered sumoylation of DNA topoisomerase I in the nuclei of scleroderma fibroblasts

✍ Scribed by Xiaodong Zhou, Wei Lin, Filemon K Tan, Shervin Assassi…

Book ID: 120705930
Publisher: BioMed Central
Year: 2011
Tongue: English
Weight: 953 KB
Volume: 13
Category: Article
ISSN: 1478-6354
DOI: 10.1186/ar3435

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Anti-DNA topoisomerase I autoantibodies

Anti-DNA topoisomerase I autoantibodies bind directly to the cell surface of fibroblasts in patients with systemic sclerosis

✍ J-L Senécal, J Hénault, M Tremblay, I Clément, Y Raymond 📂 Article 📅 2004 🏛 BioMed Central 🌐 English ⚖ 391 KB

Direct binding of anti–DNA topoisomerase

Direct binding of anti–DNA topoisomerase I autoantibodies to the cell surface of fibroblasts in patients with systemic sclerosis

✍ Jill Hénault; Mélanie Tremblay; Isabelle Clément; Yves Raymond; Jean-Luc Senécal 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 265 KB 👁 2 views

## Abstract ## Objective Fibroblasts play a crucial role in the development of systemic sclerosis (SSc), and antifibroblast antibodies (AFAs) capable of inducing a proinflammatory phenotype in fibroblasts have been detected in the sera of SSc patients. This study examined the prevalence of AFAs in

The production of chromosomal alteration

The production of chromosomal alterations in human lymphocytes by drugs known to interfere with the activity of DNA topoisomerase II. I. m -AMSA

✍ Andersson, H.C.; Kihlman, B.A. 📂 Article 📅 1989 🏛 Oxford University Press 🌐 English ⚖ 783 KB