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Decreased brain levels of 2′,3′-cyclic nucleotide-3′-phosphodiesterase in Down syndrome and Alzheimer’s disease

✍ Scribed by Roman Vlkolinský; Nigel Cairns; Michael Fountoulakis; Gert Lubec


Book ID
117412166
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
125 KB
Volume
22
Category
Article
ISSN
0197-4580

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✍ M. Gravel; D. DeAngelis; P. E. Braun 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 566 KB

We have isolated a cDNA coding for the larger isoform of the rat brain 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP2), a protein associated with myelination in the central nervous system (CNS). The complete 420 amino acid sequence was deduced from the nucleotide sequence of the cDNA. Sequence c