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Decreased adenylate cyclase responsiveness of transformed cells correlates with the presence of a viral transforming protein

โœ Scribed by Suzanne K. Beckner


Book ID
115915353
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
441 KB
Volume
166
Category
Article
ISSN
0014-5793

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The herpes simplex type 1 biochemically transformed human cell line, HB-1, was fused with thymidine kinase deficient rodent cells, and 18 hybrids were isolated using the HAT-ouabain selection system. The selected enzyme, viral thymidine kinase, was present in all 18 hybrids. In 16 of 18 hybrids the