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A viral K-RAS protein increases the stimulability of adenylate cyclase by cholera toxin in NRK cells

โœ Scribed by Douglas J. Franks; James F. Whitfield; Jon P. Durkin

Book ID
115760581
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
362 KB
Volume
147
Category
Article
ISSN
0006-291X

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Viral P21 Ki-RAS protein: A potent intracellular mitogen that stimulates adenylate cyclase activity in early G1 phase of cultured rat cells
โœ Douglas J. Franks; James F. Whitfield; Jon P. Durkin ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 428 KB ๐Ÿ‘ 1 views

Rat kidney (NRK) cells infected with a temperature-sensitive mutant of the Kirsten sarcoma virus were arrested in the Go/G1 phase of their cell cycle by incubation in serum-deficient medium at a p21-inactivating temperature of 41 "C. These quiescent ts K-NRK cells were then stimulated to transit GI