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Decrease of neuronal nitric oxide synthase in the cerebellum of aged rats

✍ Scribed by Wen-Jen Yu; Shiow-Wen Juang; Jie-Jen Lee; Tsang-Pai Liu; Juei-Tang Cheng

Book ID
117471033
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
126 KB
Volume
291
Category
Article
ISSN
0304-3940

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✍ Masayuki Ikeda; Hiroshi Komachi; Ikuko Sato; Toshiyuki Himi; Tatsuhiko Yuasa; Se πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 42 KB πŸ‘ 2 views

A free radical, nitric oxide (NO), besides being a messenger molecule in the brain, becomes a neurotoxin if overproduced. We recently reported that methylmercury (MeHg) induces neuronal NO synthase (nNOS) in Purkinje cells. In the present study, we examined the distribution and the mechanism of nNOS