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Decrease in yeast glucose-6-phosphate dehydrogenase activity due to oxygen free radicals

โœ Scribed by Ioan Florea Dumitru; Marina Tamara Nechifor


Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
522 KB
Volume
26
Category
Article
ISSN
0020-711X

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Marked decrease in specific activity con
โœ Xiao-Tao Wang; Veronica M.S. Lam; Paul C. Engel ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 171 KB

Clones overexpressing clinical glucose 6-phosphate dehydrogenase (G6PD) mutants Union (c.1360C>T/p.Arg454Cys) and Andalus (c.1361G>A/p.Arg454His), have been constructed. These abolish a salt bridge between Arg454 and Asp 286. One mutant is reportedly a Class II clinical variant and the other a Class