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Decrease in basal dopamine levels in the nucleus accumbens shell during daily drug-seeking behaviour in rats

โœ Scribed by M.A.F.M Gerrits; P Petromilli; H.G.M Westenberg; G Di Chiara; J.M van Ree

Book ID
113997631
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
554 KB
Volume
924
Category
Article
ISSN
0006-8993

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โœ L. H. Parsons; A. D. Smith; Dr. J. B. Justice Jr. ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 743 KB

Rats were treated for 10 days with cocaine (20 mgkg, i.p.1 followed by either 1 or 10 days of abstinence. On the test day a microdialysis method was performed in which dopamine (DA) was added to the perfusate at concentrations above and below the expected extracellular concentration (0,2.5, 5, and 1