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Decoupling Two-Dimensional NMR Spectroscopy in Both Dimensions: Pure Shift NOESY and COSY

✍ Scribed by Dr. Juan A. Aguilar; Adam A. Colbourne; Dr. Julia Cassani; Dr. Mathias Nilsson; Prof. Gareth A. Morris

Book ID: 112000736
Publisher: John Wiley and Sons
Year: 2012
Tongue: English
Weight: 824 KB
Volume: 51
Category: Article
ISSN: 0044-8249
DOI: 10.1002/anie.201108888

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## Abstract Intracerebral glucose resonance was directly detected and resolved __in vivo__ by two‐dimensional shift‐correlated (COSY) ^1^H NMR spectroscopy in anesthetized rats (__n__ = 4). The relative changes in brain glucose concentration were measured by volume integration of the α‐D‐glucose cr