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Deconstruction of p53 functions and regulation

โœ Scribed by Haupt, Ygal; Robles, Ana I; Prives, Carol; Rotter, Varda

Book ID
110067260
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
218 KB
Volume
21
Category
Article
ISSN
0950-9232

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## Abstract The tumor suppressor p53 is frequently mutated in cancer. We have investigated the regulation of P53 in p53 wild type mouse hepatoma cells (line 55.1c), in p53 heterozygeously mutated cells (56.1b) and in p53 defective cells (lines 56.1d, 70.4 and HUH7) under various experimental settin