Deconstructing the cell cycle
β Scribed by Martin, Sophie
- Book ID
- 109959626
- Publisher
- Nature Publishing Group
- Year
- 2011
- Tongue
- English
- Weight
- 110 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1471-0072
- DOI
- 10.1038/nrm3205
No coin nor oath required. For personal study only.
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## Abstract This is a progress report of an attempt to deconstruct the signaling network underlying cell cycle control in the mouse Y1 adrenocortical cell line, aiming to uncover ACTH growth regulatory pathways. Y1 adrenocortical tumor cells possess amplified and overexpressed cβKiβras protoβoncoge
An overriding objective in cell biology is to be able to relate properties of particular molecular components to cell behavioral functions and even physiology. In the "traditional" mode of molecular cell biology, this objective has been tackled on a molecule-by-molecule basis, and in the "future" mo