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Deconjugative aldol-cyclization sequence for the construction of substituted 2-methoxytetrahydrofurans

โœ Scribed by Paul Galatsis; Jeffrey J. Manwell


Book ID
103409931
Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
223 KB
Volume
36
Category
Article
ISSN
0040-4039

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Aldol-cyclization reaction sequence for
โœ Michael A. Calter; Priyantha M. Sugathapala; Cheng Zhu ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 194 KB

The aldol reactions of ct-diazo-13-ketoesters with a variety of aldehydes produced adducts which underwent Rh(II)-catalyzed O-H insertion reaction to yield highly substituted tetrahydrofurans. Alkylation and decarboxylation of these tetrahydrofurans formed a wide