Decomposition rate control of PLLA plate by heat treatment

✍ Scribed by Masafumi Nakagawa; Fumio Teraoka; Taiji Sohmura

• Book ID: 101596060
• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: English
• Weight: 467 KB
• Volume: 119
• Category: Article
• ISSN: 0021-8995
• DOI: 10.1002/app.32931

✦ Synopsis

Abstract

It is difficult to control the decomposition rate and the mechanical property of scaffolds after forming the poly(L‐lactide) (PLLA) scaffolds. The purpose of this study is to control the decomposition rate and mechanical properties of the PLLA plate after forming. We carried out accelerated decomposition experiments using the enzyme on the (PLLA) with various crystallinity, which were prepared by changing the heat treatment condition, and elucidated the relationship between the crystallinity and the decomposition rate. A high positive correlation was observed between the heat treatment temperature and the crystallinity. A high negative correlation was observed between the crystallinity and the decomposition rate. Using the obtained empirical formula, it became possible to calculate the required period to decompose a certain amount of the PLLA if the heat treatment temperature was known. Changing the crystallinity of the PLLA plate could arbitrarily control the decomposition rate of the PLLA plate after forming. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2011