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Decline in mitochondrial bioenergetics underlies central insulin resistance in streptozocin-induced model of sporadic Alzheimer's disease

✍ Scribed by Correia, Sónia; Perry, George; Zhu, Xiongwei; Smith, Mark; Moreira, Paula

Book ID
122540624
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
50 KB
Volume
7
Category
Article
ISSN
1552-5260

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## SPECIFIC AIMS Insulin resistance, a proximal cause of Type II diabetes (a non-insulin-dependent form of diabetes mellitus (NIDDM)), is associated with an increased relative risk for Alzheimer's disease (AD). To clarify how NIDDM may influence Alzheimer's disease (AD) neuropathology, we explore t