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Decision Theoretic Designs for Phase II Clinical Trials with Multiple Outcomes

โœ Scribed by Nigel Stallard; Peter F. Thall; John Whitehead


Book ID
110724620
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
812 KB
Volume
55
Category
Article
ISSN
0006-341X

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Optimal three-stage designs for phase II
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The objective of a phase II cancer clinical trial is to screen a treatment that can produce a similar or better response rate compared to the current treatment results. This screening is usually carried out in two stages as proposed by Simon. For ineffective treatment, the trial should terminate at