Deciphering the mysteries of RNA-containing lupus antigens
β Scribed by Ethan A. Lerner; Michael R. Lerner; John A. Hardin; Charles A. Janeway Jr.; Joan A. Steitz
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 485 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0004-3591
No coin nor oath required. For personal study only.
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## Abstract ## Objective Many lupus autoantigens contain small, highly structured RNAs, and studies have shown that the RNA components of lupus autoantigens activate production of type I interferon by dendritic cells (DCs) in vitro via the Tollβlike receptor (TLR)βmyeloid differentiation factor 88
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