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Deciphering the Language of the Genome

✍ Scribed by John W. Bodnar; Jeffrey Killian; Michael Nagle; Suneil Ramchandani


Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
294 KB
Volume
189
Category
Article
ISSN
0022-5193

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✦ Synopsis


The non-coding DNA in eukaryotic genomes encodes a language which programs organismal growth and development. We show that a linguistic and cryptographic approach can be used to deduce the syntax of this programming language for gene regulation and to compile a dictionary of enhancers which form its words.


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## Abstract Nucleoli are plurifunctional nuclear domains involved in the regulation of several major cellular processes such as ribosome biogenesis, the biogenesis of non‐ribosomal ribonucleoprotein complexes, cell cycle, and cellular aging. Until recently, the protein content of nucleoli was poorl