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Decarboxylation via Addition of Water to a Carboxyl Group: Acid Catalysis of Pyrrole-2-Carboxylic Acid

โœ Scribed by Mundle, Scott O. C.; Kluger, Ronald


Book ID
115472777
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
132 KB
Volume
131
Category
Article
ISSN
0002-7863

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A simple methodology for the conversion of substituted N-aryl-c-lactam 2/3-carboxylic acids to substituted N-aryl-diformylated pyrroles has been developed. Several c-lactam 2/3-carboxylic acids were subjected to Vilsmeier reagent and substituted diformylated pyrroles are isolated in one-step process