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Debrisoquine hydroxylation in Parkinson's disease

✍ Scribed by M. J. Steiger; P. Lledo; N. P. Quinn; C. D. Marsden; P. Turner; P. G. Jenner

Book ID
114783681
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
592 KB
Volume
86
Category
Article
ISSN
0001-6314

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## Abstract Impaired debrisoquine metabolism resulting from defects in the cytochrome P450 __CYP2D6__‐debrisoquine hydroxylase gene has been shown to be associated with the development of Parkinson's disease(PD). We studied two polymorphisms in this gene in 207 Chinese PD patients and 227 control s