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De Novo Synthesis of Tamiflu via a Catalytic Asymmetric Ring-Opening of meso-Aziridines with TMSN3.

✍ Scribed by Yuhei Fukuta; Tsuyoshi Mita; Nobuhisa Fukuda; Motomu Kanai; Masakatsu Shibasaki


Publisher
John Wiley and Sons
Year
2006
Weight
51 KB
Volume
37
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Catalytic Asymmetri
✍ Yingjie Xu; Luqing Lin; Motomu Kanai; Shigeki Matsunaga; Masakatsu Shibasaki πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons βš– 39 KB

## Abstract Fused as well as alkyl‐disubstituted aziridines undergo ring opening under catalysis of a complex derived from a 1:1:1 mixture of Broensted basic alkoxide La(OiPr)~3~, Lewis acidic triflate Yb(OTf)~3~, and axially chiral Schiff base BBN.