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De Novo Synthesis of a Methylene-Bridged Neu5Ac-α-(2,3)-Gal C -Disaccharide
✍ Scribed by Notz, Wolfgang; Hartel, Christian; Waldscheck, Bernhard; Schmidt, Richard R.
- Book ID
- 127277870
- Publisher
- American Chemical Society
- Year
- 2001
- Tongue
- English
- Weight
- 179 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0022-3263
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📜 SIMILAR VOLUMES
A position isomer of ganglioside GD3 has been synthesized in which N-acetylneuraminic acid (Neu5Ac) is linked alpha-glycosidically at C-9 of the Neu5Ac residue of the ganglioside GM3, structure. The coupling of 2-(trimethylsilyl)ethyl O-(6-O-benzoyl-beta-D-galactopyranosyl)-(1----4)-2,6-di-O-benzoyl
Glycopepfide (I), Neu5A~2-3Gall~l-4GlcNA~l-2Maactl-Ser, was synthesized using a chemoenzymatic strategy. Gal~l-4GlcNAcl~l\*2Man Ifisacd~ide was ~ using glycosidase assisted oligom:x:lutride synthesis. After coupling of this trisacchaxide with a sefine defivstive by chemical glycosylstion, sialic add