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De novo enzymes: from computational design to mRNA display

✍ Scribed by Misha V. Golynskiy; Burckhard Seelig


Book ID
113932312
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
293 KB
Volume
28
Category
Article
ISSN
0167-7799

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## Abstract Shigellosis, a bacterial disease, causes the death of more than one million people per year. Extensive studies of __Shigella flexneri__ have recognized tRNA‐guanine transglycosylase (TGT, ECβ€…2.4.2.29) as one of the key enzymes involved in the regulation of bacterial virulence. Based on