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From “carpet” mechanism to de-novo designed diastereomeric cell-selective antimicrobial peptides

✍ Scribed by Yechiel Shai; Ziv Oren

Book ID
117408104
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
223 KB
Volume
22
Category
Article
ISSN
0196-9781

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Cell selectivity and mechanism of action
Cell selectivity and mechanism of action of short antimicrobial peptides designed from the cell-penetrating peptide Pep-1
✍ Wan Long Zhu; Kyung-Soo Hahm; Song Yub Shin 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 208 KB

## Abstract Pep‐1‐K (PK) is a good cell‐selective antimicrobial peptide designed from cell‐penetrating peptide Pep‐1. To develop novel short antimicrobial peptides with higher cell selectivity and shorter length compared with PK, several PK analogs were designed by the deletion, addition and/or sub