𝔖 Bobbio Scriptorium
✦   LIBER   ✦

De novo biosynthesis of nucleotides and of nucleic acids in different regions of developing rat brain: Effect of undernutrition

✍ Scribed by I. Serra; A. Vanella; M. Avitabile; M. L. Barcellona; R. Avola; Prof. A. M. Giuffrida

Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
476 KB
Volume
8
Category
Article
ISSN
0360-4012

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The effect of undernutrition on the de novo biosynthesis of nucleic acids in cerebral hemispheres, cerebellum, and brain stem of rats at different days of postnatal development was studied. The experiments were carried out in vitro by measuring the incorporation of [^14^C]‐formate into the adenine nucleotide of the acid‐soluble fraction of RNA and DNA, as well as into the thymine of DNA.

The results obtained indicate that undernutrition during fetal and postnatal development impairs the de novo synthesis of the purine nucleotides of RNA and DNA at 5 days of age and delays it thereafter in the various brain regions examined, particularly in the cerebellum.

πŸ“œ SIMILAR VOLUMES

Effect of undernutrition on some enzymes
Effect of undernutrition on some enzymes of purine metabolism in different regions of developing rat brain
✍ A. Vanella; M. L. Barcellona; M. Avitabile; R. Avola; N. Ragusa; I. Serra; Prof. πŸ“‚ Article πŸ“… 1983 πŸ› John Wiley and Sons 🌐 English βš– 450 KB πŸ‘ 1 views

The effect of undemutrition on the activity of some enzymes involved in purine metabolism, ie, adenosine aminohydrolase, adenylate aminohydrolase, and inosine phosphorylase in cerebral hemispheres, cerebellum, and brain stem of rats at different days of postnatal development was studied. Adenosine a

Development and iron-dependent expressio
Development and iron-dependent expression of hephaestin in different brain regions of rats
✍ Zhong-Ming Qian; Yan-Zhong Chang; Li Zhu; Lei Yang; Jun-Rong Du; Kwok-Ping Ho; Q πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 235 KB πŸ‘ 1 views

## Abstract It has been suggested that Hephaestin (Heph), a newly discovered ceruloplasmin homologue, is necessary for iron egress from the enterocytes into circulation via interacting with ferroportin1 (FP1). Based on the putative function of Heph, and the similarity between the process of iron tr

The modulatory effects of ellagic acid a
The modulatory effects of ellagic acid and vitamin E succinate on TCDD-induced oxidative stress in different brain regions of rats after subchronic exposure
✍ Ezdihar A. Hassoun; Jennifer Vodhanel; Ahmed Abushaban πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 136 KB πŸ‘ 2 views

## Abstract The effects of ellagic acid (EA) and vitamin E succinate (VES) on 2,3,7,8‐tetrachlorodibenzo‐__p__‐dioxin (TCDD)‐induced oxidative stress in different brain regions of rats have been studied after subchronic exposure to the compounds. TCDD was administered to groups of rats at a dose of