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Daxx interacts with HIV-1 integrase and inhibits lentiviral gene expression

✍ Scribed by Lu Huang; Guan-lan Xu; Jian-qi Zhang; Ling Tian; Jing-lun Xue; Jin-zhong Chen; William Jia


Book ID
116297016
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
490 KB
Volume
373
Category
Article
ISSN
0006-291X

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## Abstract ## Background HIV‐1 integrase (IN) is an interesting target for the gene therapy of AIDS. Although the __in vivo__ functions are not well characterized, it is thought that IN has pleiotropic effects and plays a central role in the interplay between the virus and the host cell. Expressi