Daunorubicin efflux against a concentrat
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H. Sipko MΓΌlder; Jan Lankelma; Henk Dekker; Henk J. Broxterman; Herbert M. Pined
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Article
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1994
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John Wiley and Sons
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French
β 948 KB
Multidrug-resistant, human non-small-cell lung carcinoma SW-I573/ZR120 (2RI2O) cells, not containing the drug efflux pump P-&coprotein (Pgp), have reduced initial daunorubicin (DN) accumulation rates and decreased cellular steady-state drug concentrations. Previously we found indications of the pres