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Non-P-glycoprotein mediated mechanism for multidrug resistance precedes P-glycoprotein expression during in vitro selection for doxorubicin resistance in a human lung cancer cell line


Book ID
122088715
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
312 KB
Volume
7
Category
Article
ISSN
0169-5002

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Multidrug resistance-1 and p-glycoprotei
✍ James J. Wyman; Abby M. Hornstein; Patricia A. Meitner; Solida Mak; Patrick Verd πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 English βš– 574 KB

## Abstract We report on two chondrosarcoma cell lines, FS and AQ, that may be used as models of multidrug resistance in chondrosarcoma. Multidrug resistance‐1 expression was assayed with reverse transcription‐polymerase chain reaction. Immunostaining for the multidrug resistance‐1 product, P‐glyco