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Daunomycin-polypeptide conjugates with antitumor activity

✍ Scribed by Rita Szabó; Zoltán Bánóczi; Gábor Mező; Orsolya Láng; László Kőhidai; Ferenc Hudecz


Book ID
116275039
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
946 KB
Volume
1798
Category
Article
ISSN
0005-2736

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Preparation of four daunomycin-monoclona
✍ J. Gallego; M. R. Price; R. W. Baldwin 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 French ⚖ 806 KB

## Abstract As an approach to developing more specific anti‐tumour therapeutic agents, daunomycin has been covalently linked to the human tumour localizing, murine monoclonal antibody 79IT/36. Four procedures for coupling drug to antibody were investigated. The sugar amino group of daunomycin was m