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Dasatinib for the treatment of Philadelphia chromosome-positive leukemias

✍ Scribed by Santos, Fabio P S; Cortes, Jorge

Book ID
120012289
Publisher
Informa plc
Year
2012
Tongue
English
Weight
478 KB
Volume
13
Category
Article
ISSN
1465-6566

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Dasatinib treatment for Philadelphia chr
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## Abstract Dasatinib is a highly potent Bcr‐Abl inhibitor that is approved for the treatment of imatinib‐resistant or ‐intolerant chronic myeloid leukemia (CML) and Philadelphia chromosome‐positive acute lymphoblastic leukemia. Across a series of phase 2 and 3 trials, dasatinib was associated with