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DARPP-32 Mediates Activation of PI3K Signaling and Resistance to Gefitinib in Gastric Cancer

✍ Scribed by Zhu, Shoum ;Belkhiri, Abbes ;Zaika, Alexander ;El-Rifai, Wael

Book ID
122229776
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
98 KB
Volume
140
Category
Article
ISSN
0016-5085

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## Abstract Herein, we investigated the survival roles of Fak, Src, MEK/Erk, and PI3‐K/Akt‐1 in intestinal epithelial cancer cells (HCT116, HT29, and T84), in comparison to undifferentiated and differentiated intestinal epithelial cells (IECs). We report that: (1) cancer cells display striking anoi