Daphnezomines H, I, J, and K, New Daphnilactone-type and Yuzurimine-type Alkaloids from Daphniphyllum humile
β Scribed by Hiroshi Morita; Naotoshi Yoshida; Jun'ichi Kobayashi
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- French
- Weight
- 203 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0040-4020
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β¦ Synopsis
AbstractΓDaphnezomines H (1), I (2), J (3), and K (4), four new alkaloids possessing a daphnilactone-type (1 and 2) or a yuzurimine-type skeleton (3 and 4) have been isolated from the leaves (1), stems (2) and fruits (3 and 4) of Daphniphyllum humile, respectively, and the structures including relative stereochemistry were elucidated on the basis of spectroscopic data.
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## Abstract The MeOH extract from the flowers of __Bellis perennis__ was found to show pancreaticβlipase inhibitory activity (__IC__~50~ 455β ΞΌg/ml). From the extract, seven new triterpene saponins named perennisaponins G (**1**; __IC__~50~ 163β ΞΌM), H (**2**; 137β ΞΌM), I (**3**; 147β ΞΌM), J (**4**; 14