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Dapagliflozin: a sodium glucose cotransporter 2 inhibitor in development for type 2 diabetes

✍ Scribed by Abd A. Tahrani; Anthony H. Barnett


Book ID
107697255
Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
879 KB
Volume
1
Category
Article
ISSN
1869-6953

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## Abstract The human kidney has a key role in the regulation of blood glucose predominantly by reabsorption of glucose from the glomerular filtrate via sodium glucose co‐transporter 2 (SGLT‐2) channels. These are expressed in the proximal renal tubules and are blocked by SGLT‐2 inhibitors, which a