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DA agonists - Non-Ergot derivaties: Pramipexole


Book ID
102506021
Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
71 KB
Volume
17
Category
Article
ISSN
0885-3185

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DA agonists - Non-Ergot derivaties: Apom
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Ropinirole is a selective dopamine (DA) agonist with nonergoline structure. 1,2 It interacts with D2-like receptors in vitro and in vivo, showing greatest affinity for the D3 subtype, with little or no interaction with other neurotransmitter receptors. Ropinirole produces alterations in motor behavi

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Lisuride is an alpha-amino-ergoline with D2 receptor agonist properties and has no apparent D1 receptor effects. Similar to most ergotamine derivatives, lisuride also has 5-HT2 activity. In animal models of Parkinson's disease (PD), lisuride antagonizes reserpine-induced akinesia and induces rotatio