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D4 polymorphisms in schizophrenic patients treated with clozapine

✍ Scribed by Shaikh, S.; Kerwin, R.; Sham, P.; Sharma, T.; Collier, D.

Book ID: 122589646
Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 202 KB
Volume: 15
Category: Article
ISSN: 0920-9964
DOI: 10.1016/0920-9964(95)95514-A

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## Abstract We have examined the hypothesis that a variable number of tandem repeats in the third cytoplasmic loop of the dopamine D4 receptor influences clinical response to clozapine using a sample of 189 schizophrenic patients. Alleles of the 48‐bp repeat, which range from two to ten copies in t