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D2 dopamine receptor antisense increases the activity and mRNA of tyrosine hydroxylase and aromatic l-amino acid decarboxylase in mouse brain

โœ Scribed by Maria Hadjiconstantinou; Norton H. Neff; Long-Wu Zhou; Benjamin Weiss


Book ID
116126033
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
409 KB
Volume
217
Category
Article
ISSN
0304-3940

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Aromatic l-amino acid decarboxylase (AADC) and tyrosine hydroxylase (TH) are involved in the synthesis of dopamine and other monoamine neurotransmitters, and their activities can be regulated by a number of physiological stimuli. An interesting finding has been that (2)-deprenyl and some other irrev