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D-Serine metabolism: new insights into the modulation of D-amino acid oxidase activity

โœ Scribed by Sacchi, Silvia


Book ID
121869437
Publisher
Portland Press
Year
2013
Tongue
English
Weight
275 KB
Volume
41
Category
Article
ISSN
0300-5127

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## Abstract Dโ€serine is an endogenous Nโ€methylโ€Dโ€aspartate (NMDA) receptor coagonist. It is synthesized from Lโ€serine by serine racemase (SRR), but many aspects of its metabolism remain unclear, especially in the forebrain, which lacks active Dโ€amino acid oxidase (DAO), the major Dโ€serine degradati