d-Glucose Suppression of Tyrosine Aminotransferase in Rat-Hepatoma Cells Grown in Culture
β Scribed by David Mendelson; Albert Grossman; Amal Boctor
- Book ID
- 115112951
- Publisher
- John Wiley and Sons
- Year
- 1971
- Tongue
- English
- Weight
- 965 KB
- Volume
- 24
- Category
- Article
- ISSN
- 1432-1327
No coin nor oath required. For personal study only.
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## Abstract Theophylline, a cyclic nucleotide phosphodiesterase inhibitor, increases the rate of tyrosine aminotransferase (TAT) degradation in rat hepatoma tissue culture (HTC) cells. Theophylline (0.1β10 mM) causes a twoβ to fiveβfold increase in intracellular cAMP concentration but a 30β60% decr
## Abstract The role of the nucleus in bringing about the induction of tyrosine aminotransferase (TAT) by glucocorticosteroid hormone and its deinduction upon steroid removal has been studied in enucleated rat hepatoma tissue culture cells (FU5β5). Both processes require the presence of the nucleus