Cyvadic in advanced soft tissue sarcoma: A randomized study comparing two schedules: A study of the EORTC soft tissue and bone sarcoma group
β Scribed by Prof. Dr. H. M. Pinedo; V. H. C. Bramwell; H. T. Mouridsen; R. Somers; C. P. J. Vendrik; A. Santoro; J. Buesa; Th. Wagener; A. T. van Oosterom; J. A. M. van Unnik; R. Sylvester; M. de Pauw; D. Thomas; O. Bonadonna
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 671 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0008-543X
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Of 357 patients with soft tissue sarcomas (STSs) who were registered between 1981 and 1986 in the CWS-81 study, 21 (5.8%) were younger than 1 year of age. Six cases were probably of congenital origin since they were diagnosed in the 1st month of life. There was no difference in clinical grouping (st
## Abstract ## BACKGROUND Irinotecan (CPTβ11) is a novel antineoplastic agent that takes effect by inhibiting topoisomerase I. The Italian Soft Tissue Sarcoma (STS) Committee performed a multiinstitutional Phase II study to evaluate its effect on STS. ## METHODS Over a 2βyear period between 2002